通过外泌体介导的靶向CRISPR-Cas12a系统（EMT-Cas12a）实现HIV-1潜伏病毒DNA的体外及体内清除，同时恢复CD4+ T细胞功能，并展现无显著脱靶效应。 目前治疗HIV感染的方法包括传统的联合抗逆转录病毒疗法（cART）和免疫疗法，这些方法可以有效抑制病毒复制，但无法 ...

**Note: the release below is a special early release from the European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024, Barcelona, Spain, 27-30 April). Please credit the ...

In an ongoing clinical trial, researchers are testing whether just one dose of a new gene therapy that might effectively cure human immunodeficiency virus (HIV) infections is safe in humans. According ...

The first in-human trial of a CRISPR Cas system delivered by adeno-associated virus 9 gene therapy to treat HIV was able to target only the intended DNA and cleared the blood within 6 months.

An early-stage clinical trial raises hope for a new, single-dose HIV therapy that uses CRISPR, the famous gene-editing system. When you purchase through links on our site, we may earn an affiliate ...

A new way to eradicate HIV from the body could one day be turned into a cure for infection by this virus, although it hasn’t yet been shown to work in people. The strategy uses a relatively recent ...

CRISPR is being used in an experimental effort to eliminate the virus that causes AIDS. The gene-editing technology CRISPR has been used to change the genes of human babies, to modify animals, and to ...

In a provocative first step toward an elusive end to a devastating disease that has claimed 40 million lives, three patients have received CRISPR gene-editing therapies in an effort to eradicate HIV ...

Since the first reported cases in 1981, the human immunodeficiency virus (HIV) infected approximately 86 million people and resulted in the deaths of tens of millions of people from acquired ...