A breakthrough live-cell sensor makes DNA repair visible as it happens, unlocking new possibilities in biology and medicine.

本研究系统揭示了DNA双链断裂修复后的一个被长期忽视的层面：染色质结构与基因功能的不可逆改变。这种结构性与功能性损伤可稳定地传递给子代细胞，形成一种可遗传的基因表达缺陷，被作者定义为“染色质疲劳（chromatin ...

After two decades in the making, scientists have cracked the code on a drug that can repair DNA, setting the scene for a new ...

Cedars-Sinai scientists have created a new experimental drug called TY1 that helps the body repair damaged DNA and restore ...

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key ...

Failure to repair DNA damage can result in DNA lesions and mutations that are a driving factors in cancer development. Recent work has identified a function for DNA damage repair mechanism beyond ...

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key repair process called homologous recombination, the cell uses loops in its ...

In a quiet lab at Utrecht University, researchers have built a tool that lets you watch one of life’s most serious crises ...

The sensor lets researchers watch DNA damage and repair as it happens in living cells and organisms, making studies possible.